The CR2 research group focuses on early detection, prevention, and restoration of age-related brain and neural dysfunction. The group identifies novel fluid-based and electrophysiological biomarkers of neural aging and develops high-sensitivity, non-invasive diagnostic platforms supported by multi-biomarker prediction algorithms. In parallel, CR2 elucidates molecular and cellular mechanisms of neurodegeneration to discover targets that suppress neuronal damage and designs subtype-specific therapeutic strategies for major neurodegenerative disorders. By integrating regenerative targets, gene- and cell-based therapies, and neurostimulation bioelectronic technologies with optimized delivery systems, the group advances translational platforms for neural circuit repair, functional recovery, and clinical application.